Zusammenfassung
Die Verwendung von Stammzellen, iPS-Zellen sowie der Einsatz gentechnischer Methoden wie dem Genome Editing stellen für die Regenerative Medizin prinzipiell Möglichkeiten für die Entwicklung neuer Therapien dar. Die Umsetzung solcher Therapien wirft nicht nur naturwissenschaftlich-technische und medizinische Fragen auf, sondern auch ethische, rechtliche, soziale und ökonomische. Die erfolgreiche Realisierung regenerativmedizinischer Therapien ist daher auf eine disziplinübergreifende Herangehensweise angewiesen. Im Rahmen eines interdisziplinären und internationalen Symposiums sowie einer BMBF-Klausurwoche wurden die Aspekte der Verwendung von Stammzellen, iPS-Zellen sowie des Genome Editings diskutiert. Im Mittelpunkt standen u.a. die arzneimittelrechtliche Handhabung, verfassungsrechtliche und philosophische Fragen in Bezug auf die Kommerzialisierbarkeit menschlicher Körpersubstanzen sowie patentrechtliche Fragen im Umgang mit menschlichen Stammzellen und der Verfahren des Genome Editings.
Mit Beiträgen von
Insa S. Schröder; Susanne Müller und Timo Faltus; Inesa Chmurec; Tereza Hendl; Calvin Wai Loon Ho; Kalina Kamenova; Delphine Pichereau und Emmanuelle Rial-Sebbag; Hannah Schickl; Elena Buglo und Stephan Zuchner; Jochen Taupitz und Juliane Boscheinen; Winfried Kluth; Susanne Beck und Frederike Seitz; Timo Faltus; Rosario Isasi; Katrin Vohland, Julia Diekämper, Alexandra Moormann, Tobias Nettke und Wiebke Rössig; Hans Zillmann und Matthias Kaufmann; Ulrich Storz; Timo Faltus.
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- „... embryonic stem cell research. Currently, iPS cells are widely used in the industry to examine diseases in ...” „... laboratories, rather than directly in the patient1 (disease modelling),2 to screen small molecules and test ...” „... could develop teratoma6 and are not free from the risk of certain other health conditions7. Therefore ...”
- „... , together with the development of diseases on a worldwide scale during the last years. In 2020, mortality ...” „... from chronic diseases will drop to about 75% of the total mortality worldwide.1 Hereafter 80% of ...” „... non-communicable diseases should be eradicated.2 To face this challenge, biomedical research deploys new ...”
- „... therapeutics would constitute a major treatment modality for degenerative diseases like Parkinson’s ...” „... emerge as a major modality for treating the degenerative diseases of an aging population, but it may take ...” „... , Sociology of Health & Illness 2014, 670 f. 10 Lau/Ogbogu/Taylor/Stafinski/Menon/ Caulfield, Stem Cell ...”
- „... improving human health and well-being.2 The regulation of human genome editing continues to be, by far, a ...” „... approaches to embryonic stem cell and cloning research in 50 countries, European Journal of Health Law 2006 ...” „... derived from oocyte spindle transfer to prevent mitochondrial disease, Reproductive BioMedicine Online ...”
- „... knowledge for the treatment of diseases, which points back to health protection.37 However, even this ...” „... weighting of health protection over human dignity The destruction argument seems to underlie also the ...” „... of the enormous potential of research involving hESC for health protection, the Patent Office ...”
- „... ., Therapeutic Potential of Stem Cells Strategy for Cardiovascular Diseases, Stem Cells Int. 2016; 2016: 4285938 ...” „... to treat patient with degenerative eye disease, Nature 2014, doi:10.1038/ nature.2014.15897. 15 ...” „... pluripotent stem cells for monogenic disease modelling and therapy, World Journal of Stem Cells 2016, 118 ff ...”
- „... in adult mice corrects a disease mutation and phenotype, Nature Biotechnology 2014, 551. 4 Harper ...” „... structure and function 2017, 1 (2). 9 Nading, The lively ethics of global health GMOs: The case of the ...” „... Oxitec mosquito, BioSocieties 2015, 24 (25). 10 World Health Organisation (WHO): Yellow fever fact sheet ...”
- „... tobacco products, which might increase the public health burden of smoking Further, Broad’s outlicensing ...” „... disease, and provided the respective licensee has the capacity and intent to fully exercise such license ...”